Parenchymal Renal Disease and High Blood Pressure (Hypertension )

Parenchymal Renal Disease

Parenchymal Renal Disease

Parenchymal renal disease is most often the result of damage caused by hypertension. Hypertension causes the vessels within the kidneys to become damaged, eventually leading to kidney failure.

Hypertension and parenchymal renal disease often go hand-in-hand as the association between the two conditions are well known. Hypertension, the medical term for high blood pressure, is known to cause damage to the kidneys, often resulting in chronic renal disease. The kidneys become damaged because they play an essential role when it comes to maintaining proper blood pressure. High blood pressure occurs when the blood vessels become narrowed, causing an increase in pressure against the vessels’ walls as blood is forcefully pumped through them.

Hypertension and Parenchymal Renal Disease

It’s estimated, more than 25,000 new cases of chronic renal disease are diagnosed every year in the United States as a result of hypertension. Hypertension is the leading cause of chronic renal disease. When chronic renal disease, or kidney failure, occurs a patient must undergo dialysis until a kidney transplant is received.

As hypertension causes the heart to work harder, the blood vessels eventually become damaged due to the force of the blood flow. This causes the vessels within the kidneys to become damaged as well. As this occurs, the kidneys no longer receive adequate blood supply, which leads to kidney damage. As the kidneys become damaged, they are no longer able to remove wastes and extra fluids in the body, which can raise the blood pressure even higher.

Symptoms of Chronic Renal Disease

Most often, symptoms of early kidney damage aren’t experienced, causing the damage to continue as the condition is left untreated. Most often, chronic renal disease is diagnosed from a person’s glomerular filtration rate (GFR,) which is a measurement of how well the kidneys are working to remove wastes from the blood. As creatinine (used to break down muscle cells) levels are measured within the blood, the GFR is estimated. This allows chronic renal disease to be properly diagnosed because when the kidneys aren’t functioning properly, creatinine levels within the blood begin to rise. Normally, creatinine is taken out of the blood and exits the body in urine.


What Are Symptoms of Nephritis

What are the symptoms of nephritis?

What are the symptoms of nephritis?

What are the symptoms of nephritis? Nephritis are many points that the symptoms of various types of nephritis is not the same. Now are some common symptoms of nephritis. Symptomssuch as acute nephritis, chronic nephritis, purpura nephritis.

Nephritis symptoms: oliguria. More to oliguria or progressive oliguria, even anuria.Accompanied by gross hematuria, duration ranging from microscopic hematuria persists, theurine in patients with acute glomerulonephritis.

Nephritis symptoms: edema. About half of the patients at the beginning of oliguria, edema,heavy on the face and lower extremities. Edema are hard to dismiss.

Nephritis symptoms: high blood pressure. The onset of some patients with hypertension, but also in the process after the onset hypertension, blood pressure was persistent and difficult toown decline.

Nephritis symptoms: impaired renal function. Showed a persistent increase the characteristicsof the disease. Glomerular filtration rate was significantly lower and renal tubular dysfunctionexist.

There is another obvious symptoms of nephritis, because no symptoms so they are calledoccult nephritis. Occult nephritis majority of patients had no obvious symptoms and signs, onlysome patients may have atypical manifestations of backache, fatigue, gross hematuria. Themain clinical features of abnormal urine, abnormal urine can be expressed in three forms:

① persistent mild to moderate proteinuria, urinary protein + ~ + +, 24h urinary protein less than 1g,particles in the Urine tube, and can have a small amount of red blood cells <5/HP>. Pathological changes mostly mild mesangial hyperplasia or focal mesangial proliferative.

② continuous orintermittent hematuria main difference between the microscopic examination of urinary red blood cell deformity mainly. Often the incentives under the influence of fever, pharyngitis, fatigue,cold, drug injury, there – too gross stunned focal hyperplasia.

③ persistent proteinuria andhematuria, and sometimes also edema, blood pressure, but when the incentives after, but alsoback to the original occult state. These patients prognosis is poor, slow development of renal insufficiency. Pathological changes were more pronounced mesangial cell proliferation, membrane proliferative, membranous glomerulonephritis and focal sclerosis, nephritis early.

What Symptoms of Hypertensive Nephropathy

What symptoms of Hypertensive Nephropathy

What symptoms of Hypertensive Nephropathy

Hypertension is a condition when your blood pressure is recorded consistently at the level of 140/90 mmHg or higher. Most of the time, hypertension does not show any symptoms. The problem is that Hypertension is not just a cause of kidney disease, but it’s also a result of damage created by the kidney disease. High blood pressure makes your heart work harder and damages your blood vessels. As the blood vessels in your heart become damaged, they lose their effectiveness in screening the wastes from your body. This increases the fluids in your body and increases your blood pressure even more.

What are the symptoms of Hypertensive Nephropathy?

In the early stage of Hypertensive Nephropathy, increased nocturnal enuresis usually is the typical symptom. Long-term high blood pressure causes renal arteriole damage which will give rise to urine concentration dysfunction of renal tubule. As a result, frequent urination appears. For these patients, they usually have to get up in the night to urinate for at least two to three times. At that time, if patients do urine routine test, micro-albumin will be found in the urine.

Foamy urine also is one of the early symptoms and it means there are a lot of protein in patients urine

Changed urine color

For patients with Hypertensive Nephropathy, their urine usually appears to be dark brown, water where flesh is washed and cloudy.

Urine output too much or too less

For healthy people, the average urine volume is 1500 milliliter and four to eight times a day. If people have sharp increase or decrease of urine volume without fever, sweating and excessively drinking, then they should go to hospital to do examination, so as to find out whether there is renal damage.


Patients with Hypertensive Nephropathy usually have swelling in their face and around their eyes in the morning. Besides, after they have a good rest, swelling will disappear. Moreover, patients with serious this disease, then swelling may appear in their lower limbs, lumbosacral portion and inner ankles.

Back pain

Once people have causeless backache, they should go to hospital to exam their kidneys.

Symptoms Of Kidney Stones with Back Pain

back pain in Kidney stones are common – five to 10 in 100 people are affected by pain associated with kidney stones at some point in their life. Most people who get kidney stones for the first time are aged between 20 and 50.

Symptoms usually occur if the kidney stone:

gets stuck in your kidney

starts to travel down the ureter (tube that attaches each kidney to the bladder) – the ureter is a narrow tube and the kidney stone causes pain as it tries to pass through

causes an infection

Common symptoms of kidney stones include:

intense pain in the back or side of your abdomen or occasionally in your groin, which may last for minutes or hours, with intervals inbetween when there is no pain

feeling restless and unable to lie still

nausea (feeling sick)

blood in your urine, which is often caused by the stone scratching the ureter

cloudy or smelly urine

a burning sensation when you urinate

a high temperature (fever) of 38°C (100.4°F) or over

feeling like you need to urinate more often, even if you do not need to

pain when you urinate

It can be difficult to arrive at the cause of back pain, but if your pain began after an aerobics class then the likeliest cause will be a muscular sprain or pull.

This type of pain tends to be made worse by movement and eased by taking a hot bath, it gradually settles after a few days.

Kidney stone pain is described as excruciating, often linked with nausea or vomiting, may be associated with blood in the urine and is a pain that makes you restless and want to move about with it.

What Symptoms of Kidney Disease

Many people may be in the early stages of kidney disease and not have any indication something is wrong with their kidneys. There are certain symptoms, however, that could be a sign you have kidney failure, whether it is acute renal failure or hereditary such as polycystic kidney disease (PKD). When kidney failure (also called renal failure) is detected in the early stages, there are steps you can take to help slow the progression of kidney disease and improve your quality of life.

Here is a list of twelve such symptoms you should look out for:

Nausea and vomiting

The build-up of waste products in your blood in kidney disease can also cause nausea and vomiting.

Kidney failure symptoms from damage to the kidneys:

Making more or less urine than usual

Blood in the urine (typically only seen through a microscope)

Urine that is foamy or bubbly (may be seen when protein is in the urine)

Blood in the urine

This is a symptom of kidney disease which is a definite cause for concern. There may be other reasons, but it is advisable to visit your doctor in case you notice it.


Kidneys remove wastes and extra fluid from the body. When they are unable to do so, this extra fluid will build up causing swelling in your hands, feet, ankles and/or your face.


Healthy kidneys make a hormone called erythropoietin (a-rith’-ro-po’-uh-tin) that tells your body to make oxygen-carrying red blood cells. As the kidneys fail, they make less erythropoietin. With fewer red blood cells to carry oxygen, your muscles and brain become tired very quickly. This condition is called anemia, and it can be treated.

Skin Rash/Itching

Kidneys remove wastes from the bloodstream. When the kidneys fail, the buildup of wastes in your blood can cause severe itching.

Shortness of breath

Kidney disease causes fluid to build up in the lungs. And also, anaemia, a common side-effect of kidney disease, starves your body of oxygen. You may have trouble catching your breath due to these factors.

Pain in the back or sides

Some cases of kidney disease may cause pain. You may feel a severe cramping pain that spreads from the lower back into the groin if there is a kidney stone in the ureter. Pain may also be related to polycystic kidney disease, an inherited kidney disorder, which causes many fluid-filled cysts in the kidneys. Interstitial cystitis, a chronic inflammation of the bladder wall, causes chronic pain and discomfort.